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Other noncoding RNAs, such as long non-coding RNAs (lncRNA), have also been shown to be under epigenetic control and to have a role in regulating EMT.
This replication program appears to be under epigenetic control through mechanisms that are still poorly understood.
Lastly, regulatory T cells (Treg) that express Foxp3 are known to be under epigenetic control.
However, the gene has been shown to be under epigenetic control (Halme et al. 2004; Octavio et al. 2009).
Another way TEs may modify gene expression is to sensitize a gene to be under epigenetic control.
Since the expression of MHC-I and MHC-II can be under epigenetic control [ 2], we assessed these aspects in our model using epigenetic drugs in vivo.
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Attempts have been made to study patterns of gene expression that are associated with variability in behavior that is under epigenetic control.
It is clear that one of the key regulators of vascular function, endothelial nitric oxide synthase (eNOS) is under epigenetic control by several mechanisms, including DNA methylation [ 15].
It is therefore possible, that also in P. pastoris the transition between the yeast and the filamentous form is under epigenetic control.
On the other hand, many transposons are under epigenetic control, as reviewed by Bucher et al. (this issue), which makes the question of a direct or indirect epigenetic stress memory an interesting, but difficult-to-investigate chicken-and-egg problem.
Together, these findings reveal that cubilin and megalin mRNA expression is under epigenetic control and thus point to new avenues for overcoming pathological suppression of these genes through targeting of epigenetic regulatory processes.
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