If the objective is too unclear to define with respect to the data, try to create intermediate results to help your teams be more effective.
However, it is unclear to what extent subjectively defined preference levels (e.g., most preferred brand) modulate activation in brain regions that are typically involved in reward processing.
In some cases chiropractic is already considered to be part of "usual care," so if the treatment is to provide chiropractic services, it would be unclear how to define "usual care" in the control arm.
An additional confounding issue is that tumor markers may be used in applications other than diagnosis, and in these situations it may be unclear how to define the target condition or clinical sensitivity and specificity.
Since it is unclear how to define the notion of a weak solution to this equation, we regularize the noise and introduce a family of approximations.
It is unclear how to define, and achieve, max-min fairness in the presence of such constraints.
It is unclear how to define patients potentially benefiting from de-escalated treatment, whether a positive smoking history impacts survival data and what kind of de-escalation might be best.
The understanding of the definition of ACS among PCCN still appears to be unclear as in 2006, 33.3% defined ACS solely on a value, i.e., how high the IAP reading needs to be and did not relate it to the presence of organ dysfunction.
Whenever origins are unclear, we must define a new gene family to encompass those genes, even though they may not date back to the latest common ancestor of bilaterians.
First, it is unclear which cutoff scores should be used to define impairment.
It's unclear how they define "terror-prone", but it would almost certainly describe Syrians, who, combined with Afghans and Somalis, account for half of the world's refugees.
