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Interestingly, our data indicate that E. muris seems to be unable to activate known NLRs.
We thus hypothesized that strains where wild type DegS would be replaced by DegS S76D should be unable to activate processes that are normally stimulated by non-phosphorylated DegU, and probably overly stimulate processes that require phosphorylated DegU.
Indeed, these axons might be too far anterior to the source of Wnt in the tail, and thus be unable to activate the non-canonical pathway to promote termination.
A few patients noted that severe depression could be so overwhelming that they would be unable to activate or engage in aspects of the therapeutic space.
Db/ db mice show reduced energy metabolism and lower body temperature and may be unable to activate thermogenesis to maintain body heat when their food intake is restricted.
Perhaps, IFNγ might be unable to activate p21 to stop the cell cycle, suggesting a possible participation in breast cancer development.
Similar(47)
RSV was unable to activate PRDIII luciferase reporter activity in the cells transfected with empty vector or in those reconstituted with IKKγΔ (Figure 5D).
Unlike E2F1, E2F3 is unable to activate mTORC1, suggesting that growth activity could be restricted to individual E2F members.
As expected, MAVS was unable to activate NF-κB-driven luciferase reporter activity in IKKγ−/− MEFs, and mediated a 4-fold increase in IKKγ-WT transfectants (Figure 3B).
In contrast, tumor cells are unable to activate this protective response due to uncontrolled activation of growth pathways by oncogenic mutations.
In keeping with this observation, ERF.D.1 and ERF.D.2 are lacking the acidic activator domain and accordingly are unable to activate the synthetic GCC box promoter.
More suggestions(16)
be unable to implement
be unable to ignite
become unable to activate
be unable to send
be unable to switch
be unable to supervise
be unable to keep
be unable to use
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be ready to activate
be unable to pay
be unable to continue
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be necessary to activate
be unable to attract
be unable to survive
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