This suggests an extracellular localisation for the proteins, which is typical of cell wall invertases [ 16].
These networks are typical of cell systems and the majority of nodes have few links in such an arrangement, but a few nodes have numerous links, thereby ensuring that the system is fully connected.
This is typical of cell cycle arrest, primarily in G1, and as Figure 2 suggested, this cell cycle arrest is likely to be caused by a p53-mediated increase in p21 expression in wild-type cells (Waldman et al, 1995; Vassilev et al, 2004).
Anchoring was typical of cells which were CD133 positive, but CD34 negative.
This result was typical of cells obtained from rat hippocampus and cortex.
The mesenchymal movement is typical of cells displaying an elongated morphology in a 3D environment; it requires integrin attachment to the extracellular matrix, formation of focal contacts and pericellular proteolysis.
Although we did not evaluate if the detached cells treated with Tzb showed irregular chromatin condensation in the nucleus –which is typical of cells dying by APCD (ACDII -, the fact that Tzb-induced macroautophagy was concomitant with a reduction in SKBR3 cell number provides evidence that Tzb-induced cell death is not an obligatory outcome of Tzb-induced macroautophagy.
In contrast, some carcinoma cells can move very fast with an amoeboid shape [8], [9]; in vitro studies in 3D environments have shown that this movement is typical of cells with a rounded morphology and is associated with the formation of actin cortical rings and membrane blebbings.
The acquisition of migratory and invasive capacities is typical of cells undergoing EMT (Thiery et al, 2009).
Such behavior is typical of cell-cycle-arrested senescent cells, a phenotype where telomere shortening is believed to be one of the critical players [ 3, 4].
