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Proteins down-regulated in two of three experiments were considered less likely to be true substrates for MARCH-VIII.
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The anionic form of the α-amino group is assumed to be the true substrate for the transaldimination reaction.
Depending on fibre source, this may also be true for the substrate available for microbial growth, and can lead to a decreased diversity, which in turn may indicate a decreased resistance to "invading microbes".
Thus, the strong dependence of inhibition strength on the type of substrate used seems to also be true for EGs.
This was true for substrate 11 a and the usually more reactive substrate 11 b.
It may also be true that the substrate richness that underlies the developing brain's potential for plasticity also underlies its' early vulnerability.
Whether the same is true for other substrates will have to be determined in future studies.
This is true for single substrate utilization as well as for co-utilization.
First, peptide IV can be held rigidly in the active site, just as is true for any substrate that is efficiently turned over in a typical enzyme active site.
However, it remains to be seen if this relationship is true for other C-precursor substrates, including fructose, and for different animal species.
In addition, both surfaces were shown to co-adsorb the collectors, with some variation in the relative adsorbed amounts: MBT adsorbs more extensively than DTP from the solution mixture onto gold; the reverse is true for the gold:silver substrate.
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