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Although cellular senescence critically depends on the ARF/p53 pathway, emerging evidence suggests that cellular senescence can also be triggered in an ARF/p53-independent manner.
Similar to the wound-healing process, an activated response of the tumour stroma may initially be triggered in an attempt to restore tissue homeostasis.
If not overwhelmed, a dog's instincts might still be triggered in an unwanted way.
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The differences are significant in terms of the mechanisms by which attitudinal inferences may be triggered in a text.
Tumor tissue driven responses of primary T cells were paralleled by NFAT activation measured in CAR-transduced Jurkat T cells, which was shown to be triggered in a CAR and antigen-specific manner.
In addition, flare-up reactions can be triggered in a timely manner in this model.
However, protective mechanisms also can be triggered in a more rapid and transient fashion.
The resulting threshold from this approach varies over time, such that multiple 'alarms' may be triggered in a given season.
The fact that developmental competence can be triggered in a strain that is supposed to be partly refractory to developmental progression is mechanistically intriguing.
Initially, actin polymerization might also be triggered in a circular region at the rim of the coat, where Sla1, a regulator of actin nucleation, is also located.
Cardiac hypertrophy can be induced by hyperglycemia [ 24, 25] and MEK/ERK signaling could be triggered in a high-glucose environment [ 26].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com