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- As actin dimer and trimer formation is the kinetic barrier of actin polymerization, nucleation may be triggered by binding of actin mono-, di-, or trimers to the FH2 torus through weak actin binding sites.
Binding of AMP to the γ subunit, which is antagonized by ATP, activates AMPK by three complementary mechanisms: (i) allosteric activation; (ii) promotion of Thr172 phosphorylation by LKB1; (iii) inhibition of Thr172 dephosphorylation, which can also be triggered by binding of ADP [8 12].
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Rice Xa21-regulated race-specific disease resistance is triggered by binding a sulfated peptide secreted by Xoo to its LRR domain [ 36].
The CP is triggered by binding of C1q to IgM or IgG antibodies which bind to antigen, which in turn is translated into activation of the serine proteases C1r and C1 s.
We provide evidence that insulation is triggered by binding of the ribosome binding site (RBS) to the upstream CT-rich motif.
HH-GLI signaling is triggered by binding of ligands to the transmembrane receptor patched and is subsequently mediated by transcriptional effectors belonging to the GLI family, whose function is fine tuned by a series of molecular interactions and modifications.
These functions are triggered by binding of endogenous and exogenous ligands to cannabinoid receptors (CB receptors).
Activation of each Trk receptor is triggered by binding of the cognate neurotrophin at highly specific contact regions.
Extrinsic apoptosis is triggered by binding of extracellular ligands to tumor necrosis factor receptor family members and results in the activation of the initiator caspase, caspase-8.
Branch growth is triggered by binding to the Arp2/3 complex of an additional protein, WASP, but the sequence of events required to initiate a new branch is not well understood.
TGF-β-stimulated transcription of COL1A2 is triggered by binding of a large transcription factor complex, which is composed of Smad2/3, Smad4, SP1, and the transcription factor p300 [ 43].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com