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In light of the unlikelihood of achieving bacteriocidal concentrations with tolerable doses, serious Stenotrophomonas infections should be treated with alternative antibiotics, such as fluoroquinolones or combinations of betalactam or fluoroquinolones with TMP/SMX [68].
Women who have progressed through taxane therapy can be treated with alternative microtubule inhibitors such as vinorel-bine or eribulin if they do not have prohibitive residual neuropathy.
However, most of the infections encountered in nursing homes can be treated with alternative agents that pose lesser risks of side effects and CDI [ 23, 35].
In light of the unlikelihood of achieving bacteriocidal concentrations with tolerable doses, serious Stenotrophomonas infections should be treated with alternative antibiotics, such as fluoroquinolones or combinations of betalactam or fluoroquinolones with TMP/SMX [ 68].
However, it may be argued that this scenario points to an unfavourable disease biology in patients who would not benefit from extensive surgery anyway, but would better be treated with alternative systemic treatment.
Whether patients with evidence of disease response and a long platinum-free interval (>6 months off chemotherapy) should be retreated with platinum-based chemotherapy on progression or whether they should be treated with alternative chemotherapy regimens remains unclear, and we await data to guide such decisions.
Similar(54)
When they get sick, they're treated with alternative medicine — hand-milking, massages and homeopathic teat treatments.
Ezekiel was treated with alternative remedies for two and a half weeks before he died of meningitis in 2012.
Those deemed resistant were treated with alternative agents.
The most common symptoms being treated with alternative therapies were fatigue (16.7%) and muscle weakness (16.7%).
Of these 18 patients, 11 were treated with ECF chemotherapy and seven were treated with alternative fluorouracil-based regimens.
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