Sentence examples for be toxic when administered from inspiring English sources

Stem cell factor (SCF) is a growth factor that acts through the c-Kit receptor tyrosine kinase to elicit hematopoietic progenitor expansion but can be toxic when administered in vivo because it concurrently activates mast cells.

On the other hand, ebselen, (PhSe 2, and (PhTe 2 can be toxic when administered at high doses.

Wild-type SOD1 (WT) can acquire some of the same properties as mutant SOD1 when oxidized and stripped of metal cofactors; these preparations have also been shown to be toxic when administered to cells [ 1– 5].

Although 3 mg kg−1 indomethacin has previously been found to be toxic when administered by gavage (Masferrer et al, 2000), we did not observe any toxicity using intra-peritoneal delivery.

Until recently, the polymyxin class was mainly used via inhalation to treat high-density respiratory tract colonization due to MDR P. aeruginosa in patients with cystic fibrosis since this class was thought to be unacceptably toxic when administered parenterally.

Plastics often contain additives that can be toxic when released.

Although essential, both can be toxic when in excess [ 34- 37].

The Molecusol vehicle was unexpectedly toxic when administered i.p., but there was no toxicity from NITP dissolved in Molecusol when administered orally.

In mice (a nocturnal species) the peak in S phase occurs at 1.00 am and Topo I poisons are profoundly toxic when administered at 0200 hours (15% survival) compared to 1400 hours (90% survival; reviewed in Rich et al, 2002).

It is plausible to infer that the ethanol extract of Petroselinum crispum is not toxic when administered orally at doses of 10-100 mg/kg for 8 weeks in rats.

These results confirm that C20-20 is not toxic when administered in vivo in the retina of C57Bl6 mice.