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Unfortunately for the thieves, the damage to the tire proved to be too substantial for the liquid magic to do its thing.
These costs could be too substantial for individuals from poor households to bear.
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That may change later, but for now Amazon's league is too substantial to expect anything else.
But [the book's heroine] Roberta herself is too substantial to be a caricature.
Wilson was tempted to sack him, but by now Healey was too substantial a figure.
Heterogeneity in design was too substantial to identify differential treatment effects between different disease models.
But airy and crunchy as they were, rings of calamari were still too substantial for an appetizer, although their avocado salsa verde dip was notably divine.
Another explanation involves the amount of time that has elapsed since the transition from outcrossing to selfing, which in some instances may be too short for substantial changes to have occurred at the genome level [ 1].
Even if the effect of FLG mutations in subjects with a history of AD had been significant, the effect size would probably be too small for a substantial favourable effect on the predictive values of a screening procedure.
He had been cultivating a substantial beard, one that extended down to near his chest, but feared it would be too warm for Brazil.
Incentives are too few and disincentives too substantial for the drug industry to conduct such trials.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com