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Computational fluid dynamic (CFD) models must be thoroughly validated before they can be used with confidence for designing fluidized bed reactors.
Analyses of recent work suggest that the GEMs for the best studied microorganisms, new or less studied microorganisms, and also microbial communities need to be thoroughly validated with experimental data beyond simple gene essentiality and nutrient utilization capabilities.
We therefore conclude that any novel method for clinical mutation diagnostics should be thoroughly validated against massively parallel sequencing in order to provide a correct genetic analysis as basis for molecularly targeted therapy.
Therefore, our assay system might be most effective when it is used in conjunction with other screening techniques and any conjugation activities identified should be thoroughly validated in vivo.
The described findings suggest that M. suis is likely to synthesize phosphatidylglycerol and cardiolipin from exogenous fatty acids and use them as major constituents of the plasma membrane; however, the biosynthetic pathway needs to be thoroughly validated once this organism can be cultured in vitro.
The RTK pathway intersection the authors observed in MEPM cells could easily be thoroughly validated in the background of the respective mutants.
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The statistically significant predictive models were thoroughly validated using an external validation set whose activity was previously unknown.
This further supports the conclusion that RNA-Seq experiments do not require large-scale validation once the experiment and analysis pipeline have been thoroughly validated.
The discretization is thoroughly validated.
Subsequently, the models were thoroughly validated with a simulation experiment.
This distribution has been thoroughly validated for perfectly brittle materials.
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