Sentence examples for be the upstream driver from inspiring English sources
In cell cultures EMT is usually induced by growth factors including HGF, VEGF, and most commonly TGF-β, which is widely considered to be the upstream driver of EMT 25.
The program's orientation is toward 'addressing the upstream drivers that influence the political, social, cultural, economic, and environmental determinants of health and development' (6) by supporting innovative international approaches to health knowledge generation and synthesis through research, health research capacity development, and the use of evidence for health policy and practice.
Fluid flow acts to regularize this behavior by transferring energy from the upstream driver to the fluid.
However, the upstream driver signals culminating in activation of this machinery remains largely uncharacterized [ 5, 6].
However, there are a multitude of ligands (e.g. IL-6, OSM, EGF, HGF, IGF) and kinases (RTKs, JAKs, SRC family members) that initiate STAT3 activation and thus there are many potential upstream drivers that could contribute to the observed dysregulation [ 9].
Whereas upstream water consumption is the dominant driver of changes in water availability in May and December for the Huang He and Ganges Brahmaputra basin, respectively, LULCC and reservoir operations dominate the change in water availability in the Paraná basin year-round (Supplementary Fig. 7).
There are clearly multiple upstream drivers of a single downstream mediator and vice versa.
