Sentence examples for be the primary mediator from inspiring English sources
The M1 macrophage subpopulation is considered as the primary mediator of inflammation whereas the M2 macrophage subpopulation is considered to be the primary mediator of wound healing and pathologic fibrosis.
Although neurons of higher vertebrates express two nearly identical actin isoforms, ß- and γ-actin [3], ß-actin is thought to be the primary mediator of neuronal actin dynamics based on its unique post-transcriptional regulation.
Although we cannot exclude with certainty the role of t-Ag and other T'- proteins, based upon our results it is reasonable to speculate that T-Ag may be the primary mediator of a metastatic phenotype in colon cancer cells, and some of these effects may directly or indirectly be influenced by the activation of AKT/MAPK pathways [44], [45].
Increased sympathetic nervous system outflow appears to be the primary mediator of reduced blood flows to the splanchnic vasculature [ 95].
SIRT3, a mitochondrial sirtuin, appears to be the primary mediator of mitochondrial acetylation, since no significant changes in acetylation status are detectable in mice lacking SIRT4 and SIRT5 [ 14].
While VEGF seems to be the primary mediator of 20-HETE induced endothelial cell proliferation, inhibition with a VEGF antibody does not completely abrogate the mitogenic effect of 20-HETE induced
Known as osteoclasts, these cells are now widely acknowledged to be the primary mediators of periarticular bone erosion in inflammatory arthritis [95].
8, 90– 96 Apoptosis appears to play an important role in hepatocyte death in NAFLD, and free fatty acids could be the primary mediators of hepatocyte apoptosis (lipoapoptosis).
If these genes were not activated, it would be reasonable to suspect that other potent growth factors and cytokines released during lung injury could be the primary mediators of fibroproliferative lung disease.
