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Moreover, as the combined (i.e., direct plus indirect) effect of H2O2 on Kir6.2/SUR2A channels in intact cells was channel activation, the stimulatory action of H2O2 appeared to be the primary effect exerted by ROS generation on these channels.
This appears to be the primary effect of the angiostatic agents at low doses (dose rates).
Chromosomal rearrangements produce unbalanced gametes which have been thought to be the primary effect of rearrangements in speciation because of the diminished fecundity or viability of the heterozygotes [ 5].
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And that is the primary effect of the Off Broadway revival of "Isn't It Romantic," the first in New York since 1983, by the Worth Street Theater Company.
Neurotoxicity was the primary effect following inhalation exposures in acute and subchronic neurotoxicity studies in rats, in a series of specifically designed neurotoxicity studies in dogs, and in a developmental neurotoxicity study with direct inhalation exposure of dams and pups.
Using a fan to assist cooling was legal Brabham had used a small electric fan to this effect on the BT45Cs at the South American races at the start of the year and Brabham claimed that this was the primary effect of the new device.
What is the primary effect of the lut2.1 mutation?
These findings are generally incompatible with global chromatin opening being the primary effect of HDACi exposure.
It is likely that these aggregates are a secondary effect related to the hydrophobicity and overexpression of the protein, rather than being the primary effect of the mutation.
If adsorption is the primary effect, the surface area of the filters must be increased, perhaps by using beads rather than filaments.
This allows interpretation of the magnitude of any antagonism or synergism between the interventions, and would of course be essential if the interaction was the primary effect of interest.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com