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iRBC sequestration appears to be the pathogenic trigger of the placenta pathology observed in pregnant women and we have previously shown that P. berghei iRBC specifically adhere to the mouse placenta tissue.
A complex interplay of genetic and probably environmental factors could be the pathogenic trigger for MN.
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Aβ42, in contrast to Aβ40, is thought to be the pathogenic form triggering the pathological cascade in AD.
The strongest evidence to date suggests that the pro-inflammatory cytokine IL-6, which is readily detectable in the circulation of infected individuals regardless of the pathogenic trigger, is the main circulating mediator of hepatic HAMP mRNA expression [19] [22].
I think this may be the trigger".
Our results suggest that the sulfoxidation of Helix-3 methionines might be the switch for triggering the initial α-fold destabilization required for the productive pathogenic conversion.
pDC activation in the blood by self-nucleic acids is regarded as a pathogenic trigger of the autoimmune process, and a dysregulated type I IFN elevation in serum by the continuous pDCs activation amplifies the pathogenic spiral in SLE [ 12- 14].
These are the default trigger keys.
' That was the trigger.
What is the trigger of this panic?
This was the trigger.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com