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Based on this model, Fisher proposed a solution to the question of how evolution in complex organisms nevertheless occurs, namely that the more traits the organism has, and therefore the more dimensional the mutations are, the smaller must be the mutational steps.
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Lines between haplotypes represent the mutational steps between alleles.
The lengths of the lines are proportional to the mutational steps.
As shown in Figure 4, the STR haplotypes of Hg C* form a star-like network and the mutational steps are short.
A minimum-spanning network was also reconstructed based on the mutational steps between haplotypes of cpDNA.
In Figure S3, there should be two mutational steps between Hap14 and Hap05 instead of one.
Further, the observation that the chimpanzee haplotypes are many mutational steps away from the human modal haplotypes may indicate that selection pressures unique to the humans may have operated since the separation of the human and chimpanzee lineages.
c The smaller the mutational step relative to the curvature (i.e. distance from the optimum), the greater will be the proportion of mutations that are advantageous.
The problems of the mutational step size and of the evolution of organismal complexity revealed the weaknesses of evolutionary biology.
The Ns haplotypes were four mutational steps (at position 267, 268, 306, and 615) away from the Xm haplotypes.
TCS analysis identifies populations in the Alafia River system as being fifteen mutational steps away from populations from the St . Johns Riversystem.
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