Modularity debt is the most difficult kind of technical debt to quantify and manage.
"When we meet with incubator owners, they tell us this is the most difficult kind of space to find," Ms. Franzini said.
How they get aboard the last, or next to last, American helicopter to leave Saigon, how they fight and trick their way through the crowds to the American Embassy, is the most difficult kind of passage to write.
"Short of a war, this has probably been the most difficult kind of planning," said Mr. Rosenbaum, a professor of political science, "because it requires us to make sacrifices that hit the pocketbook directly.
Sexual assaults are the most difficult kind of crimes to prosecute: Of the 31percentt of cases that are reported to police, less than 2percentt result in convictions, according to the Rape, Abuse & Incest National Network.
More importantly, these results indicate that ganetespib is especially suitable for treating poorly differentiated GCs, which is the most difficult kind of GC to cure and usually has high EGFR expression.
"These are the most difficult kinds of work to restore, because the finish is so perfect," Scheidemann said.
But, although the basic understanding of nuclear weapons physics is widespread, nuclear weapons are, fortunately, the most difficult kind to produce or acquire.
Unfortunately, as Mr Barr put it, it is also "the most difficult" kind of conversation "especially for Americans to achieve".On a good day, Socrates's conversations bore all the marks of dialectic.
