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Actin cytoskeleton appears to be the master regulator of the Hippo-YAP/TAZ pathway, and multiple extracellular signals are integrated to the cytoskeleton reorganization to transduce the signals to the core of the Hippo kinases module.
It was thus suggested that HMGB1 could be the master regulator of MDSC function in mice.
»…hepcidin, turns out to be the master regulator of these iron-mediated mammalian defenses« The circulating hormone hepcidin, discovered in 2000, turns out to be the master regulator of these iron-mediated mammalian defenses (Ganz, 2011).
NapA, which is under RsrA control, seems to be the master regulator of the specific response to peroxide stress [ 50].
Mpp1 was suggested to be the master regulator of methanol-responsive genes in H. polymorpha [ 43, 44].
PPARG is a hormone receptor, which has already been demonstrated to be the master regulator of adipogenesis [ 25, 26].
Similar(40)
GCN4 is the master regulator of general amino acid control and regulates LEU3 expression among many other targets [ 7, 11, 12].
Hsp90 is the master regulator of the heat-shock response and its inhibition can up-regulate Hsp70.
Vascular endothelial growth factor (VEGF) is the master regulator of vascular growth.
The ataxia telangiectasia-mutated (ATM) protein kinase is the master regulator of the DNA double-strand break (DSB) repair pathway.
The redox gene Nrf2 (nuclear factor-erythroid 2-related factor 2) is the master regulator of the cellular antioxidant system.
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