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Candidates for this class of therapeutic agent are selected largely for their activities in other pathological conditions and our speculations as to other actions on what we suspect to be the main pathogenic pathways in DMD.
In conclusion, our data show that HCV infection could be the main pathogenic factor of lichen planus in Japanese patients.
The loss of genomic stability seems to be the main pathogenic key, appearing early in the carcinogenesis process.
Renal vascular remodeling, hyperplasia of the glomerular mesangium, and renal fibrosis have been considered to be the main pathogenic factors behind renal damage in hypertension [ 21].
In a large cohort of sarcoidosis patients with PH, Rapti et al. found pulmonary fibrosis and LV diastolic dysfunction to be the main pathogenic mechanisms of PH development [ 54].
Reactivation of latent infection after immunosuppression of the host was thought to be the main pathogenic mechanism (3 ); however, recent studies indicate that person-to-person spread might cause acute infection in susceptible persons (5 ).
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Lipopolysaccharide (LPS) is the main pathogenic component of E. coli.
Chronic hyperglycemia and the corresponding glucotoxicity are the main pathogenic mechanisms of diabetes and its complications.
Shunting of oxygen transport to the tissues is the main pathogenic feature of distributive shock [ 4].
Lipopolysaccharide (LPS) is the main pathogenic component of E.coli Gram-negative bacterium.
The H2C2O4 is the main pathogenic material secreted by S. sclerotiorum, but the effects of H2C2O4 acidity and the C2O42− ion on photosynthetic performance remain unknown.
More suggestions(15)
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CEO of Professional Science Editing for Scientists @ prosciediting.com