Sentence examples for be the main dose from inspiring English sources

The haematological toxicity seen is in keeping with previous reports, which also reported myelotoxicity to be the main dose limiting factor [ 16, 31, 32].

Abdominal pain and infective peritonitis proved to be the main dose-limiting toxicities.

The central side-effects of opioids are usually dose-related and can be the main dose-limiting side-effects in dose titration to obtain better pain control.

During Phase I evaluation of bryostatin-1, myalgia was shown to be the main dose-limiting toxicity (Philip et al, 1993; Prendiville et al, 1993; Varterasian et al, 1998), although the mechanism for this is not fully understood.

Dose dependent and cumulative peripheral neuropathy is the main dose limiting side effect of chemotherapy with vincristine.

Severe acute gastrointestinal toxicity (≥ grade 3) is the main dose limiting factor in patients receiving adjuvant three-dimensional conformal radiation therapy after surgery.

In humans, late onset diarrhea (>24 h post CPT-11 treatment) associated with intestinal damage and decreased white blood cell counts, especially decreased neutrophil counts, are the main dose limiting side effects of treatment with CPT-11 (Rivory, 1996; Rothenberg et al, 1996, 1999; Rothenberg, 1998).

Neutropenia is the main dose-limiting toxicity of docetaxel treatment.

Neutropenia is the main dose-limiting toxicity for eribulin.

Neutropenia is the main dose-limiting toxicity occurring in docetaxel treatment.

As expected from the toxicity profile of the study drugs, neutropenia was the main dose-limiting toxicity.