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Due to tremendous proliferative and regenerative capacity, stem cells and progenitor cells, which reside in synovium, bone marrow, adipose, and vasculature, are expected to be the main cell types recruited and induced by biomaterials in vivo.
Within the joint, chondrocytes may be the main cell source of NO, and iNOS expression is increased in human OA cartilage [ 29].
Because we found the mast cells to be the main cell subset expressing IL-17 in synovium from the knee, it is possible that the cells expressing IL-17 might be different, depending on the site of the joint.
In humans, natural killer (NK) cells that express the CD16 Fc γreceptor are thought to be the main cell type that could mediate ADCC of tumours (Arnould et al, 2006).
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Plasmacytoid dendritic cells (PDCs) have been suggested to be the main cells producing IFN-α [ 4], and an inducer of IFN-α has been identified in the circulation of patients with SLE [ 5].
Mucoid cells are the main cell type found in the gastric glands in the cardiac and pyloric areas of the stomach.
Generally, the neurons and glial cells are the main cell types in the CNS.
The membrane is the main cell structure, which mediates the primary interactions between the cell and the environment.
Should hUCB-MSCs have a superior effect on wound healing as compared with fibroblasts, which are the main cell source in current cell therapy products for wound healing, they may possibly replace fibroblasts.
T lymphocytes were the main cell population infiltrating the adventitia.
Macrophages are the main cell type responsible for TM clearance of pigment and debris [47].
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