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Calculated pKa data show the ring nitrogen atom (N1) to be the most basic with a pKa of 5.93 and the ring nitrogen atom (N5) with a pKa of −2.49 to be the least basic site in this structure [6].
Interestingly, neither of the potential acceptors located at (N5A and N5B) are utilised in hydrogen bonding and this is in good agreement with the pKa data that shows this ring nitrogen to be the least basic but also due to steric hindrance from the phenyl group and the existence of N4 H5…N5 intramolecular bonds from both 4 amino groups.
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Basic design is the least defined stage of the ship design process and seeks to define the optimal amidships section structure.
From a ring-theoretic point of view, these turn out to be the most basic (least interesting?) of all the Leavitt path algebras.
"That's why it is so important, as the JOBS Act loosened the strictures on capital raising, for there to be at least basic investor protections built in".
Other types of lubrication systems are available, but this approach is the most basic and the least expensive.
The LX was the most basic and least expensive model, with a 95 bhp VTi engine, priced at, while the Exclusive model was most expensive with a 110 bhp HDi Airdream engine at.
Well, that is the basic idea at least.
Ideally, the operation has to be autonomic for at least basic features such as selecting series, reformatting, slicing, and pan and zoom manipulation.
However, from 2006 EIS were more broadly implemented and at the very least basic data was collected for all accepted cases.
But many other aspects of these cases are controversial, not the least of which is the basic externalist doctrine that the contents of thoughts and meanings of expressions derive essentially from distal environmental causes, as opposed to sensory surface stimulations or even internal brain processing.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.
Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com