Sentence examples for be the initial trigger from inspiring English sources

Some transcriptional changes may contribute to increased valine content but are too slow to be the initial trigger for it (Figure S3).

Although there is a demonstrably bidirectional experimental relationship, observational data suggest that sympathetic activation may in fact be the initial trigger [ 82].

For activation of EpCAM signalling by RIP, cell cell contact, or binding of EpEX as a ligand, has been suggested to be the initial trigger [ 25].

NAD+ facilitates Gal80 binding to Gal4, while NADP+ destabilizes this interaction and appears to be the initial trigger for Gal4 activation (Kumar et al., 2008; Li et al., 2010).

Infectious agents may be the initial trigger of the production of cross-reacting antibodies (molecular mimicry) and may also induce the inflammatory 'second hit' mediated by Toll-like receptors (TLRs) [ 2].

Homophilic binding, either due to cell cell contact or EpEX as a ligand for non-cleaved EpCAM, has been shown to be the initial trigger for RIP [ 14, 25].

Therefore, we could speculate that they might be the initial triggering of silencing, resulting in loss of the transcriptional machinery that is then maintained by the recruitment of heterochromatic marks.

Indeed, as in diabetes, hyperglycemia, hyperinsulinemia and hyperlipidemia might be the initial triggers of significant cellular and molecular changes ultimately leading to cardiac functional and structural impairment, key features of the systolic and diastolic dysfunction associated with diabetic cardiomyopathy.

But road safety was the initial trigger, he says - worries about pupils darting across Monkwood Road to Chubby's and Keith Allgood's chip shop - along with complaints about litter and pupil behaviour.

In a statement, they said that while a land deal had been the initial trigger, rumours that police had killed a child sparked further anger.

"I think that might have been the initial trigger for this bloom," he said.