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In my view, OAD should be the initial treatment for type 2 diabetes as long as A1C levels of <7.0% can be achieved.
In keeping with pragmatic trial principles, minimal inclusion criteria were used to identify patients for whom vancomycin or daptomycin would be the initial treatment choice.
It has been previously suggested that conservative management should be the initial treatment of degenerative lumbar stenosis and decompressive surgery is appropriate to consider only in case of intolerable pain or disability.
Given the cost to patients and their physicians and the very limited and unproven clinical benefit of some possible brief preservation of β-cell function that might lead to improved control for a short initial period during the many years of diabetes, it seems to me that there is little clinical evidence that insulin should be the initial treatment for type 2 diabetes.
- NOM can also be the initial treatment in some cases of severe splenic trauma when the decision between NOM and OM depends on careful risk-benefit analysis for each patient as well as on the expertise of the surgeon and of the multidisciplinary team of the hospital.
An explanation could be the initial treatment with ProteoMiner beads; previously, Pernemalm et al. [ 24] evaluated the ProteoMiner technique on crude plasma and identified only 150 unique proteins by direct LC-MS/MS and GeLC-MS/MS with a start plasma volume comparable to ours.
Similar(54)
The transfusion of platelets is the initial treatment for ongoing bleeding after adequate heparin neutralization in many institutions [3, 6].
Conservative, non-invasive management is the initial treatment of choice for Achilles tendinopathy, particularly in the early phases [4].
Haemodynamic and respiratory support is the initial treatment of acute massive PE, followed by anticoagulation or, in the case of massive acute PE, fibrinolysis [12].
MTX monotherapy was the initial treatment in the T2T group by protocol.
Primary outcomes were the initial treatment response, and 7-day and 30-day mortality rates.
More suggestions(15)
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