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Immature myeloid DC such as Langerhans cells in the mucosal epithelium and interstitial DC in the subepithelial mucosal tissues are thought to be the first cell types that contact with HIV-1, which exploits the biology of DCs to spread the infection to HIV-1-specific and HIV-1-nonspecific CD4 T cells[29] [31].
Flow cytometry (Fig. 1a) and immunohistochemistry (Fig. 1b) revealed Ly6G+ PMNs to be the first cell type detectable in the ipsilateral hemisphere, independent of the duration of ischemia.
Also, the rapid coverage of such newly formed microvasculature by pericytes suggests that they may be the first cell type of the neurovascular unit to physically interact with endothelial cells [ 5].
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They appear to be the first cells infected by HIV and perhaps the source of HIV production when CD4+ cells become depleted in the patient.
"It's the first cell of a tumor".
Neutrophils are the first cell type to react in the host immune defense.
It's the first cell phone that has reached this milestone in mobile-crazy South Korea, according to Japanese business daily The Nikkei.
Metal of Honor however, is the first cell phone game I've ever seen to have cutscenes (a big step in mobile gaming).
The central R8 photoreceptor is the first cell to differentiate (for review see Morante et al. 2007, Freeman 1997).
In chapter five, Reich wrote that the family is "the first cell" of a fascist society, its "first central reactionary germ cell, the most important place of reproduction of the reactionary and conservative individual".
Osteoblastic cells were the first cell type identified as a HSC niche component.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com