Sentence examples for be the final common from inspiring English sources

ROS-mediated lipid peroxidation and DNA damage then appears to be the final common pathway for neuronal cell death [26].

While abnormalities in multiple pathways may lead to schizophrenia, an abnormality in dopamine neurotransmission is considered to be the final common abnormality.

Recent studies suggest that spreading depression could be the final common pathophysiological target for several established or investigational migraine prophylactic drugs [33].

Abnormal airway remodeling and persistent dysregulation of airway tone might be the final common pathway for different disease mechanisms, and this might explain the heterogeneity of clinical phenotypic syndromes that go under the common label of "asthma".

Removal of apoptotic cells by phagocytes is considered to be the final common event in the life of most apoptotic cells [ 23].

It is further postulated that these mediators, such as some cytokines, might be the final common pathway leading to bone loss in parenchimal liver disorders [ 7].

"Inflammation is the final common pathway for pretty much all chronic diseases," he told me.

At the histological level, renal fibrosis is the final common pathway of progressive kidney disease irrespective of the initial injury.

Methods Lotrafiban, a selective, nonpeptide antagonist of the human platelet fibrinogen receptor (glycoprotein [GP] IIb/IIIa [αIIb/β3 integrin]), blocks the binding of fibrinogen to the GP IIb/IIIa receptor, which is the final common pathway of platelet aggregation.

Our gene therapy strategy targets the apoptotic cascade, which is the final common pathway in all forms of retinitis pigmentosa.

In this manner, IKKγ is the final common shared signaling adapter upstream of the divergent IRF3 and the canonical NF-κB pathways.