Sentence examples for be the early defect from inspiring English sources

One of the reasons to cause this could be the early defect in dorsoventral patterning.

Changes in cellular signaling pathways are the early defects that have been described extensively in several animal models.

To examine what is the earliest defect(s) in the development of type 2 diabetes, investigators have used two approaches.

Another strategy to examine what is the earliest defect responsible for the development of type 2 diabetes is to prospectively follow individuals who are at high risk for the development of type 2 diabetes.

We believe this to be the cause of the early defect in osteoblast number observed in Nrf2−/− mice, as we were unable to detect any primary defect in osteoblast function.

As a result, visual defects may be the earliest evidence of general nervous system disease.

Current therapeutic strategy for the control of postprandial hyperglycemia is the inhibition of α-glucosidase and α-amylase, resulting in aggressive delay of carbohydrate digestion to absorbable monosaccharide [ 2]. α-Glucosidase inhibitor has been recognized as a therapeutic approach for modulation of postprandial hyperglycemia, which is the earliest metabolic defect to occur in type 2 diabetes.

Plants which grew multiple inflorescences as adults tended to be those which exhibited narrow first true leaves or other shoot meristem defects as seedlings (Fig. 7), indicating that the adult phenotype is likely a result of the early defect.

In both types of exposures, changes in cardiac function were the earliest observed defects.

The early defect in OFT elongation is likely to underlie the subsequent ventriculoarterial alignment defects observed in fetal Hes1−/− hearts.

In type 2 diabetes, impaired glycogen synthesis secondary to reduced glycogen synthase activity is the earliest detectable metabolic defect (39– 41).