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Systemic inflammation may be the common pathway among these diseases, explaining their high rate of prevalence together [ 33].
The notion is evolving that epigenetic changes affecting the developing immune system may be the common pathway to many purported causes [ 8, 16].
There is some evidence that acupuncture may act on the nucleus accumbens to inhibit the rise in dopamine which seems to be the common pathway for withdrawal symptoms [ 7, 8].
There is evidence that the development of bone, joints, connective tissue, innervation, vasculature, and muscle may each be implicated in the pathophysiology, and a disturbance of the overall process of medial rotation of the fetal foot may be the common pathway.
Combined treatment with EPO and Wnt1 did not provide a synergistic increase in the levels of phosphorylation of mTOR and p70S6K, but inhibition of the PI 3-K/Akt1 preventedrEPOnted EPO and Wnt1 from activating mTOR and p70S6K, suggesting that Wnt1 may be the common pathway for EPO activation of mTOR and p70S6K.
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It was suggested by the authors that obesity and insulin resistance may be the common pathways underlying lung function impairment and metabolic syndrome [ 16].
Although the regulation between Fas and ceramide is complicated, the activation of JNK is the common pathway in mediating Fas and ceramide-induced apoptosis.
Poorly controlled blood pressure is the common pathway leading to morbidity and mortality in patients with heart disease, diabetes, and renal disease.
It is provided by P. putida via the MEP (2- C-methylerythritol-4-phosphate) isoprenoid biosynthesis pathway which starts using pyruvate and glyceraldehyde-3-phosphate from central metabolism and is the common pathway in most bacteria.
The formation of TIAs precursor involves the shikimate pathway of tryptophan metabolism and MEP pathway which are the common pathways of terpene biosynthesis.
Therefore, chronic inflammation and increase in CRP level are the common pathways in the metabolic syndrome and infectious agents for promotion of atherosclerotic process.
More suggestions(15)
be the essential pathway
be the lethal pathway
be the common base
be the common complaint
be the preferred pathway
be the principal pathway
be the common method
be the common story
be the exclusive pathway
be the common currency
be the unexpected pathway
be the common solution
be the common burden
be the p38MAPK pathway
be the common way
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