Sentence examples for be that binding of from inspiring English sources

Thus, a simple working hypothesis would be that binding of α-SNAP to the CAD domain of Stim1 releases a potential inhibition by the CC1 domain.

Another possibility could be that binding of FUS and EWS is associated with RNAPII pausing, which in turn could modulate the subsequent splicing pattern of RCC1 mRNA.

The explanation for this may be that binding of anti-p65 antibody to p65 protein changes the p65 protein conformation and in turn leads to p65 losing its binding activity to the NFκB probe.

Even though the results of the present study are heterogeneous, the possible mechanism may be that binding of peptides in these HLA molecules leads to an immune response, resulting in that HLA-B*40 allele seems to be a susceptibility biomarker in the development of ALL and probably a protecting biomarker in the development of AML.

As the size of DNA fragments following sonication was determined to be approximately between 350 and 1000 bp (data not shown), an alternative explanation for the obtained results could be that binding of AtWhy2 to mtDNA is specific to certain sequences that are common to the various immunoprecipitated regions.

From the current study the indication is that binding of 17βE2 and ICI-182,780 to ERα increases the receptor binding to MS-KIF18A promoter and allows its activation, leading to an increase in message transcription.

One is that binding of FOXL2 to some of its target sites is indeed lost during cell culture.

One possible explanation for the complex binding kinetics of the activated wild-type enzyme is that binding of phenylalanine in the active site is affecting catecholamine binding.

The most unexpected finding of our study is that binding of HSF1 could result in inhibition of the transcription on a wide scale.

A plausible explanation is that binding of the ADEPs' to ClpP induces a conformational rearrangement in the peptidase that results in the diverse observed effects.

The key feature of this assay is that binding of the SH2 domain probe to its cognate phosphorylated binding sites is monitored in solution using a combination of proximity ligation and quantitative PCR technologies.