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A deterministic description based on ordinary differential equations can effectively describe the mean kinetic behaviour of genetic circuits, thus its predictions can be tested with experiments based on averages over cell populations.
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It can be trusted only to the extent that it is tested with experiments," said team member David E. Pritchard, the Cecil and Ida Green Professor of Physics at MIT, associate director of MIT's Research Laboratory for Electronics (RLE) and a principal investigator in the MIT-Harvard Center for Ultracold Atoms.
Performance of the proposed modification is tested with experiments of optimizing real-values functions and results are compared with results obtained with the original Imperialistic Competitive Algorithm, Genetic Algorithm, Particle Swarm Optimization and Simulated Annealing.
However, he says, the study's real contribution will happen once its predictions are tested with experiments.
The study demonstrates an iterative learning process in which we begin by integrating the current knowledge to build a model to generate hypothesis, which is tested with experiments to obtain novel information.
However, this has to be tested with additional experiments spanning a wider parameter range.
Such a prediction should be tested with further experiments.
The computational inferences directly form targeted hypotheses that can and should be tested with laboratory experiments.
Finally, the evaluation of omic data may refine the experimental model in order to make better predictions, which will then be tested with new experiments [ 72].
This model predicts several topological properties that mitochondrial networks should display, and thus can now be tested with directed experiments measuring network topology.
For example, the structural processing hypothesis could be tested with an experiment that manipulated the timing of the auditory stimuli so that object sounds were recognised at the same time point as spoken words.
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