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Available and emerging new agents in the treatment of anemia of heart failure will need to be tested in randomized, controlled studies.
This hypothesis must be tested in randomized trials.
FDA officials speaking at a tropical medicine conference Wednesday said experimental Ebola drugs should be tested in randomized controlled trials -- a "gold standard" form of drug assessment that involves giving some ill patients a sham treatment, or placebo.
Finally, these more tailored regimes should be tested in randomized trials.
Second, program effects will be tested in randomized controlled study and a large sample.
Optimally the effectiveness of these programs should be tested in randomized controlled intervention studies.
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ZMapp will be the first Ebola treatment that will be tested in a randomized, controlled study.
Taking a quarter-dose of three or four different medications looks like a promising strategy, but it needs to be tested in a larger, randomized trial, says Dr. Gibson.
However, the activity of this regimen needs to be tested in phase III randomized trials before it can be implemented in standard clinical practice.
Whether the identified high-risk neonates would have benefit of being treated with MV immediately after surfactant instead of INSURE has to be tested in a future randomized controlled trial.
In the final phase starting in October 2013 the system will be tested in a 6-months randomized controlled trial in Germany, Finland, Spain and Australia, involving more than 200 people.
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