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This indicates our datasets and networks represent profound ongoing inductive events and should be useful for identification of novel putative inductive signalling effectors, which can be tested for roles as embryonic mammary development regulators using either transgenic or knockout mouse models, which should soon be available for most genes via ongoing large-scale mouse genome initiatives.
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Accordingly, Raptor was tested for roles in protein synthesis and cell size control.
Our understanding of the functional significance of DAF-16/FoxO target genes in mediating DAF-16/FoxO-dependent longevity is based primarily on a study in which nearly 60 DAF-16/FoxO target genes were tested for roles in DAF-16/FoxO-dependent life span extension using RNAi-based assays.
"I thought this was a screen test for a 'female starlet' who was to be tested for possible roles and characters to be played by me in future Warhol films," Mr. Montez, who performed extensively onstage and acted for Jack Smith and other filmmakers, wrote in an e-mail.
Together, our results identify a relatively small number of genes that can be tested for speciation roles among D. melanogaster sibling species.
Various other transcriptional regulation mechanisms remain to be tested for their roles in the upregulation of the KLKs in ovarian cancer.
Using this approach, we identified several candidate genes that could be tested for a role in morph-specific fitness differences.
The phenotyping of knockout genes and the availability of that data in public databases will undoubtedly reveal new targets in the field of diabetes that can be tested for a role in patients.
In addition to known GBM drivers, the top hits list contained genes previously not associated with GBM, such as DLK2, CEACAM7 and RPL37 (Fig. 5C and Supplementary Table S3)—novel candidate genes to be tested for their role in tumorigenesis.
Thus, various reagents and compounds can be tested for their potential roles in reprogramming events.
When evidence for a coordinated network of interactions is identified, other genes known from previous research to be members of that network immediately can be considered as candidate genes to be tested for their potential role in alcohol-related traits.
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