Sentence examples for be tested by mutations from inspiring English sources

This could be tested by mutations that change only the nearest neighbors without changing tertiary interactions.

The model was tested by mutation of ten amino acid residues predicted to be important for binding and/or catalysis.

The functional importance of the selected amino acids was tested by mutation to glutamic acid, which reverses the charge of the residue while preserving its hydrophilic nature.

The role of integrin binding, specifically, was tested by mutation of two amino acids (D205A,D207A) or deletion of seven amino acids (Del202 208).

The functionality of the proximal Pit-1 response element was tested by mutation in the context of the pGL3B-MMP-1-1633/-1 construct (see Additional file 1).

This hypothesis can be tested by introducing mutations on per genome basis.

Based on sequence conservation, human variants can be tested by introducing homologous mutations in the yeast ortholog.

Because most known tumour initiators are mutagens, potential initiators can be tested by assessing their ability to induce mutations in a bacterium (Salmonella typhimurium).

Of these, RNA-OLA testing was performed successfully in 20/46 (43%), in one case only the protease mutations could be tested by RNA-OLA.

This hypothesis could be tested by further analysis of ASD-associated mutations, direct biochemical characterization of their effects, and assessment of in vivo effects on animal models.

Important residues predicted from docking were tested by point mutations and patch-clamp recordings.