Sentence examples for be targeted together from inspiring English sources

Both tmk and dut were assessed to be bacteriostatic genes [50] and since these genes belong to the same pyrimidine biosynthesis pathway, have no human homologs and are essential for the survival of Mtb, can be targeted together to produce a synergistic bactericidal effect.

One is synthetic lethality where redundant functions must be targeted together to cause cell death [ 30].

The other is induced-essential synthetic lethality where compensatory functions must be targeted together to cause cell death [ 30].

We identified the vesicles on which RIN2 was targeted together with R-Ras 38V as GFP-Rab5A-positive early endosomes.

For instance, two genes may not display phenotype if targeted individually by RNAi, however, they could have a lethal phenotype when both genes are targeted together: this phenotype is defined as synthetic.

Li et al. have shown that HDAC3 is targeted together with the A-Kinase-Anchoring proteins AKAP95 and HA95 to mitotic chromosomes to generate a hypoacetylated H3 tail as preferred template for Aurora B kinase (Li et al. 2006).

These data suggest that Dpr1 can be targeted to autophagosomes together with Atg14L.

Cross-talk between mediators must be considered and it is possible that multiple proteins will need to be targeted either sequentially or together.

Since we have also shown that TIEG1 and Runx2 proteins interact, one could speculate that complexes consisting of these two proteins could be rapidly targeted, together or separately, for proteasomal degradation.

Stella Creasy MP and Caroline Criado-Perez have been targeted now for days, together with other high profile women.

Pathway-based analyses were conducted for DNA repair genes; they were not conducted for viral infection and cell entry genes as only select genes were targeted for evaluation and together do not fully represent a pathway.