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However, the particular pathways that should be targeted to optimize therapeutic responses are unclear.
Proposals for development and future enhancements of this system should be targeted to optimize the parameters of the ELM algorithm used, so as to achieve even more efficient, more accurate and faster classification.
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In this paper a fuzzy logic based design space exploration technique is presented that is targeted to optimize a multicore architecture according to the workload requirements in order to achieve optimum balance between throughput and energy of the system.
Vancomycin serum trough levels of 5 15 μg/mL have previously been targeted to optimize clinical outcome in patients with NP, although more recent literature suggests a vancomycin trough level of 15 20 μg/mL [ 3].
This procedure is targeted to optimizing, rather than strictly minimizing the interference between the symbols such that constructive instantaneous interference is utilized in enhancing the decision variables at the receiver on a symbol-by-symbol basis so that detection is made more reliable.
Although there has been huge effort targeted to optimize the absorbing, energetic, and transport properties of the donor material, fullerenes remain as the exclusive electron acceptor in all high performance devices.
We propose that pathways other than VEGFR1 are activated and lead to BMDC infiltration, and should be targeted in order to optimize anti-VEGF therapy and prevent spontaneous metastasis.
Since gefitinib does not affect phosphorylation of the IGF-1 receptor (Fig. 6 and [ 63]), our results suggest that the antiapoptotic pathways driven by IGF-1 signalling should be targeted in order to optimize the antineoplastic effects of gefitinib.
The evidence presented here for primary cilia as a mechanosensor in bone cells highlights that they could be targeted for optimizing loading regimes and controlling the subsequent production of in vitro bone matrix and may inform clinical treatments of bone disorders caused by dysfunctional responses to loading.
Desirable changes in these attributes and microbiological safety (>5 log10 inactivation) were targeted while optimizing the TAHPP conditions as: 600 MPa at 52 °C for 10 min.
Various volatile components with different boiling points, including 3-methyl-1-butanol, 1-heptanol, ethyl caprate, ethyl laurate, ethyl hexadecanoate, and dodecanoic acid, are present in jujube extract and were selected as targets to optimize the extraction parameters, such as the water steam bubbling rate, MTBE volume, sample weight and S3DE time.
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