Sentence examples for be targeted for modifying from inspiring English sources

Our goal is to define how these key signaling switches governing cell migration can be targeted for modifying this cellular behavior, all the while recognizing the quantitative adaptations of the other pathways that will compensate for the subtotal interventions of a single pathway.

Left: Expression of a GAL4-inducible shRNA transgene against GFP (UAS-GFP-RNAi) will result in gene knockdown by degrading mRNA of fusion protein; Right: GFP fusion proteins can be targeted for ubiquitination-mediated degradation by a modified ubiquitination system called deGradFP (UAS-NSlmbvhhGFP4 ).

The precursor ions corresponding to the modified peptides were targeted for MS/MS.

FOXOs are targeted for phosphorylation by several protein kinases, which modify different sites on FOXOs that alter their subcellular location, DNA binding affinity, and transcriptional activity [ 36, 37].

Nike has been targeted for poor labour conditions in its overseas factories, Nestlé for the sale of powdered baby milk in poor countries, Monsanto for genetically modified food.

Indeed, endosymbiotic transferred genes are the prime candidates for being rapidly modified to be targeted back the transitional plastid.

Most proteins that are targeted to the proteasome for degradation are first modified by the ubiquitin (Ub) system [ 3].

AMP activated PK (AMPK) is a cellular energy sensor (Hardie, 2007) that is another attractive target for modifying mitochondrial bioenergetics in mitochondrial disease.

The N-terminus can be selectively targeted for modification when it is sufficiently accessible and not post-translationally modified.

This specificity furthermore means that in vivo, αvβ3 integrin-positive cells, including angiogenic endothelial cells, macrophages in spleen and liver, and macrophage subsets in the intestines [ 32] and also fibroblasts and macrophages that constitute the synovial lining [ 33, 34], are likely to be the target for the modified virus.

On the other hand, it has been shown that by targeting the metabolites correlated with an objective phenotype, gene targets for modifying the phenotype could be selected [ 22].