Specifically, two human proteins, i.e. neurogenic locus notch homolog protein 1 (NOTCH 1) and Rho-associated protein kinase 1 (ROCK 1), were suggested as promising regulators in the SSRI-mediated neurorecovery, which can be targeted efficiently by fluoxetine and paroxetine, respectively, as well as other SSRIs and metabolites.
Human Zip4 mRNA would not be targeted efficiently by the RNAi against mouse Zip4.
While yesterday's announcement was welcomed by development groups, there was also some caution that the money is targeted efficiently.
This study found patterns in the prevalence of risk factors to be in line with previous research [ 12– 15] therefore supporting evidence that screening in primary care should be targeted to efficiently address multiple as opposed to single health behaviours [ 30, 31] in those most at risk.
A piece of content may fulfill all other requirements of being "good," but may not be targeted efficiently or may not be targeted at all.
Furthermore, NLS-EGFP and mCherry produced by P2A-mediated cleavage were targeted most efficiently in the mouse liver as well, as evidenced by confocal microscopy (Fig. 6B).
Using this technique, we verified that P42-TAT is targeted to the brain as efficiently as when provided directly by intra-cerebroventricular injection.
However, our targeted approach efficiently enriched for genes that were targeted, at considerably lower sequencing depths.
As extracellular targets can be efficiently targeted using antibodies, we focused here on intracellular targets (assuming that peptides can be manipulated to cross the membrane [ 18, 19]).
As a consequence, PG may not be efficiently targeted to, or retained at, the desmosomes, and in turn might become available for other intracellular pools.
