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But such sanctions need to be targeted correctly.
In order to be targeted correctly, and to interact with the other motor complex proteins, GAP50 requires glycosylation at the amino‐terminus (Fauquenoy et al., 2011).
The use of RNA interference has revealed, however, that a number of cargoes (such as transferrin and Fc receptors, for example) can be targeted correctly even in the absence of AP-1B, which suggests that these proteins can move directly from the Golgi complex to the basolateral surface without crossing the endocytic routes (Gravotta et al. 2007).
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It was important to confirm that the SOD A was targeted correctly since overexpression might lead to mis-targeting or blocking of the trafficking pathway.
"To ensure that support is targeted correctly and that we achieve value for money, we operate a strict competitive contract tendering process and factor all costs into departmental spending plans.
Absolutely, if they are targeted correctly, mobilized properly and sustained effectively.
The chimeric protein was targeted correctly to mitochondria (Fig. 5B a c; Suppl. Fig. S4) and retains full fission activity (Fig. 5C).
One ES cell clone that had been targeted correctly during the first round of selection was transfected with a Cre expression plasmid and grown for 7 days in G418.
Mono-glucosylated oligosaccharides of glycoproteins are targeted by the calnexin/calreticulin cycle and after being deglucosylated by Gls II, will be targeted by GT if not correctly folded (Fig. 1b).
However, in cells of non-mesenchymal origin, most lysosomal hydrolases are still targeted correctly to the lysosome (Fig. 5) (Little et al. 1987; Owada and Neufeld 1982; Waheed et al. 1982), suggesting the existence of alternative pathways.
Young people are highly likely to view and share politically themed content – as long as it is targeted at them correctly.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com