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Additionally, the structures reveal two pockets that could be targeted by structure-based drug design.
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"We were targeted by animals.
The research for such new targets and drug chemotypes is aided by structure-based drug design.
Three of Britain's biggest building societies were targeted yesterday by internet-based carpetbaggers demanding they convert to banks.
Deoxytetrangomycin or STA1 was discovered by structure-based virtual database screening of the National Cancer Institute (NCI) database.
To ensure that the gene-based searches always reflect the most current gene structure, genes that have been structurally altered during our reannotation were targeted each evening by EGC and reprocessed to gather the latest bioinformatics data.
The structure-based molecular docking is considered a suitable approach for the development of new drugs, since this approach is targeted to specific protein and specific pathway [47].
The Nebraska Democrat was similarly targeted by D.C.-based groups on health care reform.
In silico drug screening results by structure-based screening methods strongly depend on the target protein's 3D structure (Kontoyianni et al 2005; Warren et al 2006).
Cortical structures may be focally targeted by using ring configurations.
It is frequently difficult, or even impossible, to fully describe the signals, which may be sequence- or structure-based, by which these enzyme recognize their target substrates.
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