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However, care must be taken in defining the range of gains for which our model is valid.
Given the potential caveats of RNA-seq data, caution must be taken in defining "biologically meaningful" transcript isoforms.
Therefore, without complete analysis of their targets and pathways (interactome), caution should be taken in defining the role of deregulated miRNAs in liver cancer, as well as in using miRNAs in cancer therapeutics.
Two conceptual approaches can be taken in defining dietary exposure: the decompositional approach focuses on specific nutrients and other chemical constituents of food, whereas the integrative approach emphasizes the action of whole foods or food patterns (cuisines).
It is not a criticism of the structural approach, but it does show that care needs to be taken in defining the unit of change for any given context and suggests that this might be a significant factor in people's own intuitive judgments.
Care must be taken in defining "similar patients" to avoid selection bias, either by too imprecise or too strict criteria.
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Thus, the impact of monitoring the context data must also be taken in consideration when defining the context annotations.
That professional conception of academic freedom, characterized by boycotters as impoverished, desiccated, and an alibi for neoliberal hegemony, must be left behind so that actions in violation of academic freedom narrowly defined may be taken in the name of an academic freedom suitably enlarged.
For them the scope of the defense varied in proportion to the nature of their official functions and the range of decisions that conceivably might be taken in "good faith". This "functional" approach also defined a second tier, however, at which the especially sensitive duties of certain officials -- notably judges and prosecutors -- required the continued recognition of absolute immunity.
The influences of failure modes, shear capacities and ductility of anchors were taken in account by defining exposed length.
When it's taken in moderation - usually defined conservatively as the amount in one to two cups of coffee a day - most researchers have concluded that caffeine presents little to no risk to people's health.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com