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Alteration of the p53 pathway has been reported to be systematically observed in non-small cell lung cancer with activating EGFR mutations, suggesting that p53 inactivation is required to allow expansion of a cell with EGFR pathway activation (Mounawar et al, 2007).
Indeed, recent studies have indicated that oncogenic activation of transduction cascades leads to malignant transformation, only if p53 is inactivated: alteration of the p53 pathway has been reported to be systematically observed in NSCLC with activating EGFR mutations suggesting that p53 inactivation is required to allow expansion of a cell with EGFR pathway activation (Mounawar et al, 2007).
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The males were tagged with coloured plastic labels (T-Bar extra small anchor, FF-94, FLOY TAG Inc., Seattle, WA) attached to the muscle near the dorsal fin and their behaviour was systematically observed during three observation sessions per day (morning, midday and afternoon) over 5 days starting 18 days after group formation.
Throughout the subsequent 1,000 years or so, lunar eclipses were hardly ever reported in China in marked contrast to solar obscurations, which were systematically observed during much of this period.
Galileo used his modest instrument to explore such celestial phenomena as the valleys and mountains of the Moon, the phases of Venus, and the four largest Jovian satellites, which had never been systematically observed before.
An overlap of 95% CIs was systematically observed for area.
An overlap of 95% CIs was systematically observed for area in liver.
In all provinces, the SPS, CPS and HBP were systematically observed and evaluated.
Mixtures of pararealgar and/or realgar have been systematically observed in many studies [8 10].
Nevertheless, a shift in the peak soot position toward the burner is systematically observed.
Induced mobility gains from STI and CESL stressors are systematically observed.
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