Desirability functions are suitable for formulating design constraints more precisely than inequality relations and, moreover, the global design model results in an unconstrained optimization problem.
Hence, these nine different descriptors are suitable for formulating a scoring function that can differentiate between small molecules that are likely to bind kinases (actives that have kinase-likeness) and those that are not.
As a result, C-K theory represents a good way for structuring design reasoning mostly in the conceptual phases of product innovation and development and it may be also used to explore market information, while TRIZ is suitable for formulating and refining the design problem in a structured way.
Applying the algorithm to different domains of biological interest (i.e., the S. cerevisiae peroxisome, cellular bud and cell budding) has shown that the method is suitable for formulating testable and mechanistic hypotheses about the existence of dependencies among functions.
We propose that this harmless bacterium, which is inexpensive to produce and formulate, might be suitable for topical applications as a viable alternative in the search for effective microbicides to counteract the world wide incidence of HIV infection.
Some Styrofoam glues may be formulated for use only on Styrofoam, while others may be suitable for gluing Styrofoam to other surfaces.
NLS formulated in (2) is a centralized method which may not be suitable for practical implementation.
To formulate hypotheses as to what biochemical mechanisms have the greatest control over the sunitinib-induced responses, thereby suggesting drugs that may be suitable for customized chemotherapy regimens, we applied global Sobol sensitivity analysis.
PJs should be suitable for nighttime temperatures.
May not be suitable for hyperactive children.
