Sentence examples for be successfully targeted by from inspiring English sources

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The gene encoding HPRT is located on the X-chromosome and was amongst the first genes to be successfully targeted by homologous recombination in mouse, in an attempt to model the mutation that causes Lesch-Nyhan syndrome in humans [4], [5].

Morin [ 20] estimated that only a couple of hundred loci are likely to be successfully targeted by P-elements, and that different vectors will soon be required.

We next asked whether tumor cells engrafted at a visceral site could be successfully targeted by a P-1257 formuladministeredstered via a systemic route.

A detailed roadmap of NPC disease neuropathology in mice should help to identify pathways conserved in humans that can mitigate disease and be successfully targeted by biopharmaceutical approaches.

This seemingly paradoxical situation, that a highly conserved parasite protein can be successfully targeted by the host immune system, makes sense if one imagines PfRh5 as functionally important and therefore conserved component of a host-parasite interaction complex.

In general, the ability to bind fragments in such shallow surface pockets adds confidence that similar PPIs can be successfully targeted by using fragment-based methods, thus expanding target space for small-molecule inhibition.

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Similar(53)

These results demonstrated that the tumor regions, which were identified in the in vivo MR imaging, were successfully targeted by Apt-MNC. Figure 8 Representative photographs of the brain stained with H & E and Prussian blue.

This cache was successfully targeted by IDF forces".

Websites run by the Tunisian government have been successfully targeted by Operation Tunisiaa, a cell within Anonymous' Operation Payback, in a distributed denial of service action, which dropped this image and message on several government sites before the Anon-fueled DDoS knocked them offline.

In addition, HIV-1 has been successfully targeted by artificial shRNA and miRNA-based approaches (reviewed in [25], [26]) and long-term expression of therapeutic interfering RNAs has been observed in HIV-1 infected cells [27], again arguing against a significant reduction in the RNAi capacity of infected cells.

It has been successfully targeted by small molecule kinase inhibitors and by antibodies.

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