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The spatial distribution of various hydrochemical parameters can be successfully mapped using GIS.
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Moreover, randomly selected 20-fold of paired-end reads from short insert size libraries were aligned to the assembly, and 92.75% were successfully mapped using BWA (Burrow-Wheeler Aligner, version 0.5.9-r16 40, giving a genome coverage of ~99.57%, suggesting our assembly covered most of the genome (Supplementary Tables 4 and 5).
Furthermore, the 5'-ends of these six Northern-supported sRNA candidates were successfully mapped using 5'-RACE analysis.
Rare, high-penetrance susceptibility alleles have been successfully mapped using family-based linkage studies.
Many monogenetic Mendelian disorders, including mutations in the familial breast and ovarian cancer genes BRCA1 and BRCA2, have been successfully mapped using linkage analysis [ 18, 19].
Most of the metabolic variation observed among the ecotypes was successfully mapped using this RIL population, indicating that metabolic variation can be associated with simplified polymorphic patterns at specific chromosomal regions.
Susceptibility to colon cancer 1 (Scc1) was one of the first low-penetrance cancer modifiers to be successfully mapped and cloned in mice using the AOM/DMH model (Ruivenkamp et al. 2002).
Genomic regions governing salinity stress tolerance was successfully mapped in rice using stress indices (Pandit et al. 2010, Kumar et al. 2015; Tiwari et al. 2016).
Rather than finding an excess of genetic disease with monogenic inheritance distributed throughout the population, rare monogenic recessive diseases are kindred or community specific and causative mutations have been successfully mapped in many cases using homozygosity mapping strategies[34], [35].
The use of iSPR for monitoring autoantibody binding to different citrullinated targets was first described by Lokate and coworkers [ 22], and later citrullinated B-cell epitopes in fibrinogen were successfully mapped with the use of this technology [ 23].
Of the three genes that were identified to contain shared polymorphisms (lp5, pr4.1, wrky-like-1) lp-5 was successfully mapped to linkage group 3 using mapping populations and did not show a significant deviation from expected Mendelian patterns in the FBRC-families it was segregating in (lowest P = 0.087,χ2 = 2.92 df = 1)).
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