Sentence examples for be substantially overcome from inspiring English sources

These data indicate that the N-terminal region (residues 1 25), rich in negatively charged amino acids, might severely interfere with DNA substrate binding of wild-type pol ι, but this interference could be totally ablated by the deletion of N-terminal 25 amino acids or could be substantially overcome by the low level of Mn2+.

For example, in the xTEND study, there were potential biases associated with combining self-reported (ARMHS) and clinical (HCS) measures of height and weight across cohorts, which were to be used in calculating body mass index; these biases were substantially overcome by applying correction equations to the self-report data based on previous Australian research [ 48].

We also describe how benefits from water investments could be substantially increased by overcoming design constraints, strengthening water user associations, and protecting catchments.

Thus ΔGE of such an exporter is likely to be substantially larger than that of the simple importer, large enough to overcome the positive differential-binding energy of the substrate, ΔGD s).

The lifetime fixing is preferred to overcome inadequacy in the resolving of first shortest component due to mixing different annihilation events (especially, when I 1 occurs to be substantially greater than I 3) [11] 11].

The preseason should be substantially shortened.

Yes, western consumption will be substantially reduced.

The cost will be substantially greater".

But that percentage may be substantially understated.

Those obstacles are now being overcome.

However, a Product Development Partnership to overcome this hurdle could accelerate the time lines towards when control of ETEC disease in DCs is substantially closer.