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The replication of genome-wide pharmacogenomic studies of anti-cancer agents will likely be found to be substantially more problematic than genome-wide studies examining risk of developing a cancer.
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In contrast, other types of data use, such as examining changes in rankings over time, or time-series analysis based on reviewed composites indicators, are substantially more problematic.
Choosing a sword for martial arts is substantially more problematic than choosing a decorative sword.
And they are substantially more expensive.
Maybe there is substantially more.
That's substantially more money to play in investments with.
They were substantially more educated.
Unfortunately, what he is singing is more problematic.
What is left unseen is more problematic.
But there is much that is more problematic.
Overseas campuses can be even more problematic.
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