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For a peptide with three helical sections: protonated AcA14KG3A14KG3A14K; a coiled-coil bundle with three helices side-by-side is substantially less stable than a geometry with two helices in an antiparallel coiled-coil and the third helix collinear with one of the other two.
We noted that the main impediment to efficient hiPSC differentiation was that hiPSC-derived hEB were substantially less stable and robust than those formed from hESC lines.
It is important to note that zinc-free NOS retains near full catalytic activity, although the dimer is substantially less stable.
Will there be substantially less money in the system?
(If the cap were higher, the cost to the taxpayer would be substantially less).
Losses, however, could be substantially less, and part of the amount may already be financed.
"It suggests that there may be substantially less money than anticipated for rebuilding the site.
Its forward revenue figure would be substantially less, of course.
Interestingly, PDI appears to be substantially less affected or unaffected.
RGS-GAIP was substantially less potent.
The error is substantially less when production rates are low.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com