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Evolution of both nonsynonymous and synonymous sites in protein-coding sequences, in particular, those of highly expressed genes, appears to be substantially constrained by selection for robustness to mistranslation-induced protein misfolding (Drummond and Wilke 2008; Wolf, Wolf, and Koonin 2008).
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The idea that people tend to fare best when their lives are substantially constrained or guided by their social and physical context has recently been dubbed contextualism; the contrary view, that people do best when their lives are, as much as possible, determined by the individuals themselves, is individualism (Haybron 2008c).
Aggressive oral vaccination programs in the region eliminated the domestic dog coyote RV variant by 2004, while circulation of the Texas gray fox variant was substantially constrained (18 ).
Philosophers are thus to be constrained by scientific standards.
China will also be constrained by other developments as well.
These loops of IL-3Rα are substantially shorter than their counter parts in GMRα (Figure 1A, Figure S5A), their structure and trajectory are highly constrained by the beta sandwich core.
Ought theatre be constrained by ethical considerations?
Where the great would not be constrained by the small.
Will social enterprise thrive or be constrained by Big Society?
"Not for Apple to be constrained by it.
In any case don't be constrained by my recommendations.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com