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Gene responses to RB are shown to be substantially affected in the sak1 mutant.
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Genes that were substantially affected in regulatory but not conventional T cells included those encoding Myosin-6, Egr-3, PD-1, Ptger2, Galnt14, Tox, RGS10, LIP1, Ly6f, Txk, and Tec.
The N. crassa Δ gat-1 deletion strain is substantially affected in growth on pectic substrates, unable to take up D-GalA, and impaired in D-GalA-mediated signaling events.
Genetic and biochemical analyses show that the N. crassa Δ gat-1 deletion strain is substantially affected in growth on pectic substrates and is unable to take up D-GalA from the medium.
For instance, only the secretion of lower-order factors such as IL-2 was substantially affected in the case of stimulation with potent antigens while most, if not all, effector functions triggered in response to the weakest agonists relied on faithful MHCI/CD8 interactions even at high antigen density.
It is, nevertheless, and exciting avenue with potentially far-reaching implications when it comes to regulation of cardiomyocyte cell death, particularly in the contexts of a delayed and slow-progressing response outcome of which can be substantially affected by changes in cell-to-cell variability.
Bees and other Hymenoptera can also be substantially affected by natural compounds in the environment besides ethanol.
Workforces at large tertiary care hospitals functioning as reference hospitals for persons with influenza may be substantially affected during pandemics, particularly in regard to absenteeism and associated costs.
For all these reasons, we believe that the overall conclusions of this work will not be substantially affected by possible errors in the data.
Both dentists in the community and dental organizations may be substantially affected by the implementation of any P4P program.
In general, it was found that the chloride penetration resistance can be substantially affected by the type of binder.
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