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Previous studies have shown that if balancing or prognostic factors are well chosen, increases in power can be substantial (for example, >10%).
For large ICCs, the loss in power can be substantial; for example, ICCs of 0.10, 0.20, and 0.30 would lead to a reduction in power of 4%, 9%, and 15% respectively.
However, the advantages of a benefit-harm comparison metric may be substantial, for example, in the context of complex situations where multiple outcomes are important and where patient, provider, and policymaker preferences vary [ 7].
Similar(56)
Differences between group means were substantial; for example.
The burden on the public health system has been substantial; for example, >63,000 PETs were reported in the same period.
Moreover, the effect of influenza disease in tropical countries is substantial; for example, rates of influenza-associated hospitalizations in subtropical Hong Kong approximate US estimates (13 ).
However, the improvement in precision is substantial: for example, PPI+COMBINE sees more than fivefold increase in precision at many points in the graph.
We note that if the relationship between fitness and flux is such that fitness costs of minor increases in flux are substantial, for example, if threshold selection causes fitness above the optimal flux to be zero, then this result would no longer hold.
The economic impact of Alexandrium blooms is substantial; for example, economists estimated that a large bloom in the northeastern U.S. in 2005 cost the seafood industry alone $2.7 million per week in lost revenues, with some estimates suggesting double that amount [ 6].
However, it is substantial for the stable model semantics (see Example 8).
In other situations, there can be substantial power battles, for example, when evidence calls policy into question or challenges vested economic interests.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com